Medicina (May 2023)

Primary Effusion Lymphoma, Multicentric Castleman’s Disease, and Kaposi’s Sarcoma in an HHV-8 and HIV-Positive Patient: A Case Report

  • Juan Carlos Caballero,
  • Laura Pardo,
  • Maria Socorro Rodriguez-Pinilla,
  • Miguel Angel Piris,
  • Beatriz Alvarez,
  • Laura Solan,
  • Javier Cornago,
  • Jose Luis Lopez-Lorenzo,
  • Pilar Llamas,
  • Raul Cordoba,
  • Alberto Lopez-Garcia

DOI
https://doi.org/10.3390/medicina59061049
Journal volume & issue
Vol. 59, no. 6
p. 1049

Abstract

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Primary effusion lymphoma (PEL), Kaposi’s sarcoma (KS), and multicentric Castleman’s disease (MCD) is an uncommon group of diseases included in the same spectrum with related characteristics. The coexistence of all of them in the same individual is a rare occurrence. We present the case of a 25-year-old patient diagnosed with human immunodeficiency virus (HIV) and the development of all these related pathologies. Despite the use of intensive treatment according to the latest recommendations, the evolution was unfavorable. This case reflects the need for new therapies and research in this field.

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