Nature Communications (Nov 2022)

Mode of delivery modulates the intestinal microbiota and impacts the response to vaccination

  • Emma M. de Koff,
  • Debbie van Baarle,
  • Marlies A. van Houten,
  • Marta Reyman,
  • Guy A. M. Berbers,
  • Femke van den Ham,
  • Mei Ling J. N. Chu,
  • Elisabeth A. M. Sanders,
  • Debby Bogaert,
  • Susana Fuentes

DOI
https://doi.org/10.1038/s41467-022-34155-2
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 12

Abstract

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The establishment and composition of the host microbiota is known to impact the function of the host immune response. Here the authors show that mode of delivery may impact the intestinal microbiota composition from birth and modulate the response to routine childhood vaccines.