Nature Communications (Aug 2022)

De novo protein design of photochemical reaction centers

  • Nathan M. Ennist,
  • Zhenyu Zhao,
  • Steven E. Stayrook,
  • Bohdana M. Discher,
  • P. Leslie Dutton,
  • Christopher C. Moser

DOI
https://doi.org/10.1038/s41467-022-32710-5
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

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De novo development of a simplified photosynthetic reaction center protein can clarify practical engineering principles needed to build enzymes for efficient energy conversion. Here, the authors develop an artificial photosynthetic reaction center that functions without the need for sacrificial electron donors or acceptors.