Chinese Journal of Lung Cancer (Apr 2024)

Inaugural Scalp Metastasis of Pulmonary Squamous Cell Carcinoma: 
A Rare Case Report and Literature Review

  • Wenbo HE,
  • Mingjun GAO,
  • Qinglin REN,
  • Mengmeng WANG,
  • Siding ZHOU,
  • Xiaolin WANG,
  • Yusheng SHU

DOI
https://doi.org/10.3779/j.issn.1009-3419.2024.101.11
Journal volume & issue
Vol. 27, no. 4
pp. 321 – 324

Abstract

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Distant cutaneous metastasis of primary lung squamous cell carcinoma is an exceedingly rare event, with scalp metastasis as the initial clinical presentation even rarer. Scalp skin metastases are prone to be misdiagnosed as other scalp disorders, yet their appearance signifies the deterioration and poor prognosis of lung cancer. This case report documents a female patient presenting initially with scalp folliculitis in dermatology, who was subsequently diagnosed with malignant lung tumor through radiological imaging and referred to Department of Thoracic Surgery. Pathological examination of the excised lesion from the scalp revealed distant metastasis of lung cancer. A review of similar cases reported in literature was conducted. This article aims to enhance understanding and awareness of skin metastasis in lung cancer, to emphasize the importance of this condition, and to improve early recognition and precise diagnosis. It is crucial to prevent clinical misdiagnosis and ensure appropriate treatment, finally leading to improve the prognosis of the patients.

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