Frontiers in Surgery (Jun 2023)

Appendiceal collision tumors: case reports, management and literature review

  • Giovanni Viel,
  • Francesco A. Ciarleglio,
  • Marco Frisini,
  • Stefano Marcucci,
  • Stefano Valcanover,
  • Emma Bragantini,
  • Mattia Barbareschi,
  • Liliana Mereu,
  • Saverio Tateo,
  • Elettra Merola,
  • Franco Armelao,
  • Giovanni De Pretis,
  • Marco Brolese,
  • Nicola L. Decarli,
  • Alberto Brolese

DOI
https://doi.org/10.3389/fsurg.2023.1184322
Journal volume & issue
Vol. 10

Abstract

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Appendiceal tumors are incidentally detected in 0.5% cases of appendectomy for acute appendicitis and occur in approximately 1% of all appendectomies. Here, we report two cases of appendiceal collision tumors in two asymptomatic women. In both cases, imaging revealed right-lower-quadrant abdominal masses, which were laparoscopically resected. In both cases, histological examinations revealed an appendiceal collision tumor comprising a low-grade appendiceal mucinous neoplasm and well-differentiated neuroendocrine neoplasm (NEN). For complete oncological control, right hemicolectomy was performed in one patient for the aggressive behavior of NEN; however, histology revealed no metastasis. The other patient only underwent appendectomy. No further treatment was recommended. According to the latest guidelines, exact pathology needs to be defined. Proper management indicated by a multidisciplinary team is fundamental.

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