Open Medicine (Aug 2024)

Empagliflozin improves aortic injury in obese mice by regulating fatty acid metabolism

  • Yue Lin,
  • Wang Yue,
  • Wang Cuiying,
  • Niu Shu,
  • Dong Xihong,
  • Guan Yaqing,
  • Chen Shuchun

DOI
https://doi.org/10.1515/med-2024-1012
Journal volume & issue
Vol. 19, no. 1
pp. 1581 – 6

Abstract

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Empagliflozin has been shown in clinical studies to lower the risk of adverse cardiovascular events. Using proteomics, the current study aims to determine whether empagliflozin reduces aortic alterations in obese mice and to investigate its molecular mechanism of action.

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