NeuroImage (Mar 2025)
The neural activity of auditory conscious perception
- Kate L. Christison-Lagay,
- Aya Khalaf,
- Noah C. Freedman,
- Christopher Micek,
- Sharif I. Kronemer,
- Mariana M. Gusso,
- Lauren Kim,
- Sarit Forman,
- Julia Ding,
- Mark Aksen,
- Ahmad Abdel-Aty,
- Hunki Kwon,
- Noah Markowitz,
- Erin Yeagle,
- Elizabeth Espinal,
- Jose Herrero,
- Stephan Bickel,
- James Young,
- Ashesh Mehta,
- Kun Wu,
- Jason Gerrard,
- Eyiyemisi Damisah,
- Dennis Spencer,
- Hal Blumenfeld
Affiliations
- Kate L. Christison-Lagay
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Aya Khalaf
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Noah C. Freedman
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Christopher Micek
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Sharif I. Kronemer
- Department of Neurology, Yale University, New Haven, CT 06520, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA
- Mariana M. Gusso
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Lauren Kim
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Sarit Forman
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Julia Ding
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Mark Aksen
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Ahmad Abdel-Aty
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Hunki Kwon
- Department of Neurology, Yale University, New Haven, CT 06520, USA
- Noah Markowitz
- Feinstein Institute for Medical Research, Hofstra Northwell Sch. of Med., Manhasset, NY 11030, USA
- Erin Yeagle
- Feinstein Institute for Medical Research, Hofstra Northwell Sch. of Med., Manhasset, NY 11030, USA
- Elizabeth Espinal
- Feinstein Institute for Medical Research, Hofstra Northwell Sch. of Med., Manhasset, NY 11030, USA
- Jose Herrero
- Feinstein Institute for Medical Research, Hofstra Northwell Sch. of Med., Manhasset, NY 11030, USA
- Stephan Bickel
- Department of Neurology, Hofstra Northwell School of Medicine, Manhasset, NY 11030, USA; Department of Neurosurgery, Hofstra Northwell School of Medicine, Manhasset, NY 11030, USA
- James Young
- Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA
- Ashesh Mehta
- Department of Neurosurgery, Hofstra Northwell School of Medicine, Manhasset, NY 11030, USA
- Kun Wu
- Department of Neurosurgery, Yale University, New Haven CT 06520, USA
- Jason Gerrard
- Department of Neurosurgery, Yale University, New Haven CT 06520, USA
- Eyiyemisi Damisah
- Department of Neurosurgery, Yale University, New Haven CT 06520, USA
- Dennis Spencer
- Department of Neurosurgery, Yale University, New Haven CT 06520, USA
- Hal Blumenfeld
- Department of Neurology, Yale University, New Haven, CT 06520, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA; Department of Neurology, Hofstra Northwell School of Medicine, Manhasset, NY 11030, USA; Department of Neuroscience, Yale University, New Haven, CT 06520, USA; Corresponding author at: Yale Depts. Neurology, Neuroscience, Neurosurgery, 333 Cedar Street, New Haven, CT 06520-8018, USA.
- DOI
- https://doi.org/10.1016/j.neuroimage.2025.121041
- Journal volume & issue
-
Vol. 308
p. 121041
Abstract
Although recent work has made headway in understanding the neural temporospatial dynamics of conscious perception, much of that work has focused on visual paradigms. To determine whether there are shared mechanisms for perceptual consciousness across sensory modalities, here we test within the auditory domain. Participants completed an auditory threshold task while undergoing intracranial electroencephalography. Recordings from >2,800 grey matter electrodes were analyzed for broadband gamma power (a range which reflects local neural activity). For perceived trials, we find nearly simultaneous activity in early auditory regions, the right caudal middle frontal gyrus, and the non-auditory thalamus; followed by a wave of activity that sweeps through auditory association regions into parietal and frontal cortices. For not perceived trials, significant activity is restricted to early auditory regions. These findings show the cortical and subcortical networks involved in auditory perception are similar to those observed with vision, suggesting shared mechanisms for conscious perception.
Keywords
