Journal of the International Association of Providers of AIDS Care (Dec 2022)

The Outcomes of Transition from Pediatrics to Adult Care among Adolescents and Young Adults with HIV at a Tertiary Care Center in Bangkok

  • Supattra Rungmaitree MD,
  • Nuchanat Thamniamdee MD,
  • Saranya Sachdev BSc,
  • Wanatpreeya Phongsamart MD,
  • Keswadee Lapphra MD,
  • Orasri Wittawatmongkol MD,
  • Alan Maleesatharn MBA,
  • Benjawan Khumcha BA,
  • Risa M. Hoffman MD,
  • Kulkanya Chokephaibulkit MD

DOI
https://doi.org/10.1177/23259582221143673
Journal volume & issue
Vol. 21

Abstract

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Background: Adolescents and young adults with HIV (AYHIV) are at high-risk of loss to follow up and virologic failure, particularly during transition from pediatric to adult clinics. Methods: We reviewed the medical records of AYHIV to characterize retention and virologic suppression following their transition. Results: 101 AYHIV, 97% perinatally infected, were transferred at the median age of 20 (IQR: 19-21) years. At 1-year post-transition, 92.1% were retained in care and 73.3% had viral suppression and at 2-years the retention and viral suppression were 87.1% and 76.7%, respectively. Factors associated with viral suppression were transition at ≥ 20 years of age (aOR 4.38, 95% CI 1.41-13.65) and receiving first-line ART regimen, compared to second- or third-line regimens, at transition (aOR 6.05, 95% CI 1.55-23.58). Conclusion: Transition outcomes of AYHIV in our setting were suboptimal. There is a need for interventions to support AYHIV transition during this vulnerable period.