Cancer Medicine (Feb 2023)

Recent advances in surgical strategies and liver transplantation for hepatoblastoma

  • Masaki Honda,
  • Koushi Uchida,
  • Tomoaki Irie,
  • Kazuya Hirukawa,
  • Masashi Kadohisa,
  • Keita Shimata,
  • Kaori Isono,
  • Naoki Shimojima,
  • Yasuhiko Sugawara,
  • Taizo Hibi

DOI
https://doi.org/10.1002/cam4.5300
Journal volume & issue
Vol. 12, no. 4
pp. 3909 – 3918

Abstract

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Abstract Hepatoblastoma (HB) is the most common malignant liver tumor in children. Although the development of treatment strategies with advances in chemotherapy has greatly improved the prognosis of HB, surgical resection and liver transplantation still play a vital role in the treatment of HB. In recent years, technological innovations have led to the development of new surgical approaches for HB. In this review, we describe the latest research on the surgical management of HB, including new imaging technologies, minimally invasive approaches, and the application of associating liver partition portal vein ligation for staged hepatectomy. We also discuss the current role of liver transplantation, use of ante‐situm or ex‐situ liver resection with auto‐transplantation, and management of metastatic HB.

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