WUSCHEL acts as an auxin response rheostat to maintain apical stem cells in Arabidopsis

Yanfei Ma; Andrej Miotk; Zoran Šutiković; Olga Ermakova; Christian Wenzl; Anna Medzihradszky; Christophe Gaillochet; Joachim Forner; Gözde Utan; Klaus Brackmann; Carlos S. Galván-Ampudia; Teva Vernoux; Thomas Greb; Jan U. Lohmann

doi:10.1038/s41467-019-13074-9

Nature Communications (Nov 2019)

WUSCHEL acts as an auxin response rheostat to maintain apical stem cells in Arabidopsis

Yanfei Ma,
Andrej Miotk,
Zoran Šutiković,
Olga Ermakova,
Christian Wenzl,
Anna Medzihradszky,
Christophe Gaillochet,
Joachim Forner,
Gözde Utan,
Klaus Brackmann,
Carlos S. Galván-Ampudia,
Teva Vernoux,
Thomas Greb,
Jan U. Lohmann

Affiliations

Yanfei Ma: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Andrej Miotk: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Zoran Šutiković: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Olga Ermakova: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Christian Wenzl: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Anna Medzihradszky: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Christophe Gaillochet: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Joachim Forner: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Gözde Utan: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University
Klaus Brackmann: Vienna Biocenter (VBC), Gregor Mendel Institute (GMI), Austrian Academy of Sciences
Carlos S. Galván-Ampudia: Laboratoire Reproduction et Développement des Plantes, University of Lyon, ENS de Lyon
Teva Vernoux: Laboratoire Reproduction et Développement des Plantes, University of Lyon, ENS de Lyon
Thomas Greb: Department of Developmental Physiology, Centre for Organismal Studies, Heidelberg University
Jan U. Lohmann: Department of Stem Cell Biology, Centre for Organismal Studies, Heidelberg University

DOI: https://doi.org/10.1038/s41467-019-13074-9
Journal volume & issue: Vol. 10, no. 1
pp. 1 – 11

Abstract

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Spatial control of auxin signaling maintains a balance between stem-cell self-renewal and differentiation at the plant shoot apex. Here Ma et al. show that rheostatic control of auxin response by the WUSCHEL transcription factor maintains stem cells by conferring resistance to auxin mediated differentiation.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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