Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds

Marwa Mersni; Bingqing Zhou; Guillaume Reversat; Islem Yangui; Mohamed Larbi Khouja; Alexandre Guy; Camille Oger; Jean-Marie Galano; Thierry Durand; Chokri Messaoud; Claire Vigor

Food Chemistry Advances (Oct 2022)

Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds

Marwa Mersni,
Bingqing Zhou,
Guillaume Reversat,
Islem Yangui,
Mohamed Larbi Khouja,
Alexandre Guy,
Camille Oger,
Jean-Marie Galano,
Thierry Durand,
Chokri Messaoud,
Claire Vigor

Affiliations

Marwa Mersni: University of Carthage, National Institute of Applied Sciences and Technology (INSAT), UR17ES22 Laboratory of nanobiotechnology and valorization of medicinal phytoresources, Centre Urbain Nord, BP 676, 1080, Tunis Cedex, Tunisia; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France
Bingqing Zhou: Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France
Guillaume Reversat: Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France
Islem Yangui: University of Carthage, National Institute of Applied Sciences and Technology (INSAT), UR17ES22 Laboratory of nanobiotechnology and valorization of medicinal phytoresources, Centre Urbain Nord, BP 676, 1080, Tunis Cedex, Tunisia
Mohamed Larbi Khouja: University of Carthage, National Institute of Research in Rural Engineering, Waters and Forests, BP 10, Ariana, 2080, Tunisia
Alexandre Guy: Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France
Camille Oger: Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France
Jean-Marie Galano: Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France
Thierry Durand: Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France
Chokri Messaoud: University of Carthage, National Institute of Applied Sciences and Technology (INSAT), UR17ES22 Laboratory of nanobiotechnology and valorization of medicinal phytoresources, Centre Urbain Nord, BP 676, 1080, Tunis Cedex, Tunisia; Corresponding author at: Pôle Chimie Balard Recherche Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, France, 1919 route de Mende, 34293, MONTPELLIER, cedex 5
Claire Vigor: Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France; Corresponding author at: Pôle Chimie Balard Recherche Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, France, 1919 route de Mende, 34293, MONTPELLIER, cedex 5

Journal volume & issue: Vol. 1
p. 100077

Abstract

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Phytoprostanes and phytofurans are derived from peroxidation of α-linolenic acid (ALA) the main polyunsaturated fatty acid (PUFA) found in higher plants. These compounds are considered as excellent biomarkers of oxidative degradation and have demonstrated a wide range of biological activities (e.g. protection of neuronal cells against stress, anti-inflammatory). In the present work, these new active oxylipins, were detected for the first time in Acacia cyanophylla seeds collected in Tunisia from 7 ecotypes, using LC-MS/MS technology. The main PhytoP found was ent-9-L1-PhytoP, ranged from 3.30 ng/g (N-OB ecotype) to 19.14 ng/g (B-ZO ecotype). Three PhytoFs were detected with significantly higher values than PhytoPs. Multivariate analyses indicated a significant differentiation between compounds attributed to variation in climatic factors. This first complete PhytoP and PhytoF profile shows that Acacia cyanophylla Lindl. seeds could be as a new source of bioactive compounds for therapeutic and pharmaceutical applications.

Published in Food Chemistry Advances

ISSN: 2772-753X (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Technology: Chemical technology: Food processing and manufacture
Website: https://www.journals.elsevier.com/food-chemistry-advances

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