Using different method for detection Helicobacter pylori that causing gastric cancer and compared with invasive method in the Al-Ramadi city

Abstract

The study aims at finding out the most efficient method in the diagnosis and the easiest sample in usage. The study collects 50 samples from outpatients who customarily visit the medical sight unit. The collections of the samples include biopsy tissue, blood, saliva and stool from each patient, as well as 30 samples were collected from the control group (people who are not infected). The samples of biopsy tissue are used to test (Culture, rapid urease enzyme, and histopathology) through using saliva sample of the culture test. It also uses stool samples, rapid antigen stool test (strip) . However, the serum samples were used to detect antibodies formed IgG against infection with the Helicobacter pylori . The study compared between the invasive and non- invasive. the culture test was 6% of sensitivity and 100% of specificity, the rapid urease enzyme test was 66% of sensitivity and 90% of specificity and the histopathologic test was 14% of sensitivity and 100% of specificity. The rapid stool antigen test was 54% of sensitivity and 80% of specificity then the serum ELISA test with a sensitivity of 58% and specificity of 60%. It was found after comparing invasive with non-invasive methods that the rapid urease enzyme in invasive methods is the most efficient in diagnosis , also The non-invasive methods found the rapid stool antigen test the most efficient in diagnosis .

Keywords

• helicobacter pylori