Generalized tuberculosis in association with systemic lupus erythematosus on a background of methylprednisolone pulse therapy: difficulties of diagnostics and treatment

Abstract

Systemic lupus erythematosus (SLE) and a high-dosage corticosteroid therapy both are risk factors of tuberculosis development. The clinical case presented demonstrates the difficulties of diagnostics and simultaneous therapy of comorbid diseases, which are followed by a multisystemic tuberculosis on the one hand, and a highly active SLE resulting from tubercular regimen on the other. Our experience shows the importance of antituberculosis drug prescription in accordance with a personal chemotherapy acceptability.

Keywords

• системная красная волчанка
• пульс-терапия
• милиарный туберкулез
• туберкулезный менингит
• противотуберкулезная терапия