Crystal structure of 1-methyl-3-[2,2,2-trifluoro-1-(1-methyl-1H-indol-3-yl)-1-phenylethyl]-1H-indole

Abstract

The title compound, C26H21F3N2, was prepared by the palladium-catalysed reaction of (2,2,2-trifluoroethyl)benzene with 1-methyl-1H-indole. The dihedral angle between the planes of the indole-ring systems is 52.13 (6)° and the N-methyl groups point away from each other. Three short intramolecular C—H...F contacts are observed.

Keywords

• crystal structure
• 1H-indole
• trifluoromethyl groups
• biological activity
• hydrogen bonding