Journal of Functional Biomaterials (Dec 2021)

Properties and Applications of PDMS for Biomedical Engineering: A Review

  • Inês Miranda,
  • Andrews Souza,
  • Paulo Sousa,
  • João Ribeiro,
  • Elisabete M. S. Castanheira,
  • Rui Lima,
  • Graça Minas

DOI
https://doi.org/10.3390/jfb13010002
Journal volume & issue
Vol. 13, no. 1
p. 2

Abstract

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Polydimethylsiloxane (PDMS) is an elastomer with excellent optical, electrical and mechanical properties, which makes it well-suited for several engineering applications. Due to its biocompatibility, PDMS is widely used for biomedical purposes. This widespread use has also led to the massification of the soft-lithography technique, introduced for facilitating the rapid prototyping of micro and nanostructures using elastomeric materials, most notably PDMS. This technique has allowed advances in microfluidic, electronic and biomedical fields. In this review, an overview of the properties of PDMS and some of its commonly used treatments, aiming at the suitability to those fields’ needs, are presented. Applications such as microchips in the biomedical field, replication of cardiovascular flow and medical implants are also reviewed.

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