Engineering transient dynamics of artificial cells by stochastic distribution of enzymes

Shidong Song; Alexander F. Mason; Richard A. J. Post; Marco De Corato; Rafael Mestre; N. Amy Yewdall; Shoupeng Cao; Remco W. van der Hofstad; Samuel Sanchez; Loai K. E. A. Abdelmohsen; Jan C. M. van Hest

doi:10.1038/s41467-021-27229-0

Nature Communications (Nov 2021)

Engineering transient dynamics of artificial cells by stochastic distribution of enzymes

Shidong Song,
Alexander F. Mason,
Richard A. J. Post,
Marco De Corato,
Rafael Mestre,
N. Amy Yewdall,
Shoupeng Cao,
Remco W. van der Hofstad,
Samuel Sanchez,
Loai K. E. A. Abdelmohsen,
Jan C. M. van Hest

Affiliations

Shidong Song: Department of Bio-Organic Chemistry, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology
Alexander F. Mason: Department of Bio-Organic Chemistry, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology
Richard A. J. Post: Department of Mathematics and Computer Science, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology
Marco De Corato: Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology
Rafael Mestre: Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology
N. Amy Yewdall: Department of Bio-Organic Chemistry, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology
Shoupeng Cao: Department of Bio-Organic Chemistry, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology
Remco W. van der Hofstad: Department of Mathematics and Computer Science, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology
Samuel Sanchez: Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology
Loai K. E. A. Abdelmohsen: Department of Bio-Organic Chemistry, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology
Jan C. M. van Hest: Department of Bio-Organic Chemistry, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology

DOI: https://doi.org/10.1038/s41467-021-27229-0
Journal volume & issue: Vol. 12, no. 1
pp. 1 – 9

Abstract

Read online

Here the authors develop a coacervate micromotor that can display autonomous motion as a result of stochastic distribution of propelling units. This stochastic-induced mobility is validated and explained through experiments and theory.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal