Nature Communications (Apr 2020)

An open source and reduce expenditure ROS generation strategy for chemodynamic/photodynamic synergistic therapy

  • Conghui Liu,
  • Yu Cao,
  • Yaru Cheng,
  • Dongdong Wang,
  • Tailin Xu,
  • Lei Su,
  • Xueji Zhang,
  • Haifeng Dong

DOI
https://doi.org/10.1038/s41467-020-15591-4
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 9

Abstract

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The supply of oxygen species for dynamic therapy is a major limitation. Here, the authors report on a complex of calcium peroxide with photo/chemo dynamic agents, where NIR heating causes the release of calcium peroxide to generate oxygen and hydrogen peroxide for photodynamic and chemodynamic therapy.