Case Report on Leiomyosarcoma of the Vulva: A Rare Pathology

Abstract

Leiomyosarcoma (LMS) of the vulva is rare. However it is the most common histologic subtype of vulvar sarcoma, accounting for approximately 1% of all vulvar malignancies. 1-8 Whether genetics and epigenetics play a role in pathogenesis is unclear.1 The tumor is slow-growing with non-specific symptoms, has high metastatic potential, and follows a bimodal age distribution.1-8 Diagnosis and prognosis are based upon immunohistochemical expression and criteria from early literature.1,3,5-7 The most common therapeutic approach involves radical vulvectomy with lymph node resection. The value of adjuvant chemotherapy and radiation remains unknown.1,3,5-8 Our case describes a 46-year-old Caucasian gravida 2, para 2 (G2P2) female with LMS of the left labia.

Keywords

• leiomyosarcoma
• vulva
• immunohistochemical