Romanian Journal of Laboratory Medicine (Jul 2023)

Monitoring CAR T cells in peripheral blood by flow cytometry following Tisagenlecleucel in Fundeni Clinical Institute, Bucharest

  • Popa Delia C.,
  • Sandu Horia M.,
  • Suciu Raluca,
  • Ţica Valeria G.,
  • Şerbănică Andreea,
  • Şerbănică Ionut,
  • Jercan Cristina,
  • Coriu Daniel,
  • Tanase Alina,
  • Coliţă Anca

DOI
https://doi.org/10.2478/rrlm-2023-0019
Journal volume & issue
Vol. 31, no. 3
pp. 175 – 184

Abstract

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Introduction: Over the past few years, the introduction of chimeric antigen receptor (CAR) T-cell therapy by the FDA has shown remarkable success in treating various hematologic malignancies. However, the limited response and resistance observed in some patients have hindered its broader application.

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