Nature Communications (Aug 2016)

Chromatin remodelling and antisense-mediated up-regulation of the developmental switch gene eud-1 control predatory feeding plasticity

  • Vahan Serobyan,
  • Hua Xiao,
  • Suryesh Namdeo,
  • Christian Rödelsperger,
  • Bogdan Sieriebriennikov,
  • Hanh Witte,
  • Waltraud Röseler,
  • Ralf J. Sommer

DOI
https://doi.org/10.1038/ncomms12337
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 8

Abstract

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In the nematode Pristionchus pacificus, a developmental switch, the sulfatase eud-1, controls mouth-form plasticity. Here, the authors show that mutations in two conserved histone modifying enzymes mimic the eud-1 phenotype, in part mediated by an antisense eud-1RNA, resulting in the absence of one mouth-form