Терапевтический архив (Aug 2013)

A combination of dipeptidyl peptidase-4 inhibitor and metformin in the treatment of patients with type 2 diabetes mellitus: effective control of glycemia, weight, and quantitative body composition

  • M V Shestakova,
  • O Iu Sukhareva,
  • T O Chernova,
  • I A Shmushkovich,
  • A A Aleksandrov,
  • A V Il'in,
  • I I Dedov

Journal volume & issue
Vol. 85, no. 8
pp. 49 – 55

Abstract

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AIM: To study the impact of intensified therapy with the dipeptidyl peptidase-4 (DPP-4) inhibitor vilagliptin or sulfonylurea (SU) on the control of glycemia, weight, and quantitative body composition in patients with type 2 diabetes mellitus (DM-2) who have failed to achieve compensation during metformin monotherapy/MATERIAL AND METHODS: Forty patients (mean age 55.0 (range 53.0-60.7) years; disease duration 2.0 (range 1.1-5.0) years) with poor glycemic control (7%

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