1,6-Cyclophellitol Cyclosulfates: A New Class of Irreversible Glycosidase Inhibitor

• Marta Artola,
• Liang Wu,
• Maria J. Ferraz,
• Chi-Lin Kuo,
• Lluís Raich,
• Imogen Z. Breen,
• Wendy A. Offen,
• Jeroen D. C. Codée,
• Gijsbert A. van der Marel,
• Carme Rovira,
• Johannes M. F. G. Aerts,
• Gideon J. Davies,
• Herman S. Overkleeft

Affiliations

Marta Artola

†Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands

Liang Wu

Department of Chemistry, University of York, Heslington, York, U.K.

Maria J. Ferraz

§Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Chi-Lin Kuo

§Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Lluís Raich

Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) and Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Barcelona, Spain

Imogen Z. Breen

Department of Chemistry, University of York, Heslington, York, U.K.

Wendy A. Offen

Department of Chemistry, University of York, Heslington, York, U.K.

Jeroen D. C. Codée

†Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands

Gijsbert A. van der Marel

†Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands

Carme Rovira

Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) and Institut de Química Teòrica i Computacional (IQTCUB), Universitat de Barcelona, Barcelona, Spain

Johannes M. F. G. Aerts

§Department of Medical Biochemistry, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

Gideon J. Davies

Department of Chemistry, University of York, Heslington, York, U.K.

Herman S. Overkleeft

†Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands