JPhys Materials (Jan 2022)
Roadmap on biomaterials for women’s health
- Kaitlin Fogg,
- Ning-Hsuan Tseng,
- Shelly R Peyton,
- Pieper Holeman,
- Shannon Mc Loughlin,
- John P Fisher,
- Allison Sutton,
- Ariella Shikanov,
- Juan S Gnecco,
- Katrina M Knight,
- Emily M Slaby,
- Jessica D Weaver,
- Nicole N Hashemi,
- Yali Zhang,
- Michael D House,
- Brandon J Vogt,
- Brian A Aguado,
- John C Bradford,
- Jennifer L Robinson,
- Patricia K Thomas,
- Anthony G Lau,
- Michelle L Oyen
Affiliations
- Kaitlin Fogg
- School of Chemical, Biological and Environmental Engineering, Oregon State University , United States of America
- Ning-Hsuan Tseng
- Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst , United States of America
- Shelly R Peyton
- Molecular and Cellular Biology Graduate Program, University of Massachusetts Amherst , United States of America; Department of Chemical Engineering, University of Massachusetts Amherst , MA, United States of America
- Pieper Holeman
- ORCiD
- Fischell Department of Bioengineering, University of Maryland , College Park, MD, United States of America
- Shannon Mc Loughlin
- ORCiD
- Fischell Department of Bioengineering, University of Maryland , College Park, MD, United States of America
- John P Fisher
- Fischell Department of Bioengineering, University of Maryland , College Park, MD, United States of America
- Allison Sutton
- Department of Biomedical Engineering, University of Michigan , Ann Arbor, MI 48109, United States of America
- Ariella Shikanov
- Department of Biomedical Engineering, University of Michigan , Ann Arbor, MI 48109, United States of America; Program in Cellular and Molecular Biology, University of Michigan , Ann Arbor, MI 48109, United States of America
- Juan S Gnecco
- Department of Biomedical Engineering, Tufts University , Medford, MA, United States of America; Mother Infant Research Institute, Tufts Medical Center , Boston, MA, United States of America
- Katrina M Knight
- ORCiD
- Department of Bioengineering, University of Pittsburgh , Pittsburgh, PA, United States of America
- Emily M Slaby
- School of Biological and Health Systems Engineering, Arizona State University , AZ, United States of America
- Jessica D Weaver
- School of Biological and Health Systems Engineering, Arizona State University , AZ, United States of America
- Nicole N Hashemi
- ORCiD
- Department of Mechanical Engineering, Iowa State University , Ames, IA, United States of America
- Yali Zhang
- Mother Infant Research Institute, Tufts Medical Center , Boston, MA, United States of America
- Michael D House
- ORCiD
- Mother Infant Research Institute, Tufts Medical Center , Boston, MA, United States of America; Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Tufts Medical Center , MA, United States of America
- Brandon J Vogt
- Department of Bioengineering, University of California San Diego , La Jolla, CA, United States of America; Sanford Consortium for Regenerative Medicine , La Jolla, CA, United States of America
- Brian A Aguado
- ORCiD
- Department of Bioengineering, University of California San Diego , La Jolla, CA, United States of America; Sanford Consortium for Regenerative Medicine , La Jolla, CA, United States of America
- John C Bradford
- ORCiD
- Bioengineering Graduate Program, University of Kansas , Lawrence, KS, United States of America
- Jennifer L Robinson
- ORCiD
- Bioengineering Graduate Program, University of Kansas , Lawrence, KS, United States of America; Department of Chemical and Petroleum Engineering, University of Kansas , Lawrence, KS, United States of America
- Patricia K Thomas
- The College of New Jersey, Department of Biomedical Engineering , Ewing, NJ, United States of America; Department of Biomedical Engineering, Wake Forest University School of Medicine , Winston-Salem, NC, United States of America; Virginia Tech-Wake Forest University School of Biomedical Engineering and Sciences , NC, United States of America
- Anthony G Lau
- ORCiD
- The College of New Jersey, Department of Biomedical Engineering , Ewing, NJ, United States of America
- Michelle L Oyen
- ORCiD
- Center for Women’s Health Engineering and Department of Biomedical Engineering, Washington University in St. Louis , St. Louis, MO, United States of America
- DOI
- https://doi.org/10.1088/2515-7639/ac90ee
- Journal volume & issue
-
Vol. 6,
no. 1
p. 012501
Abstract
The application of engineering tools and techniques to studying women’s health, including biomaterials-based approaches, is a research field experiencing robust growth. Biomaterials are natural or synthetic materials used to repair or replace damaged tissues or organs or replicate an organ’s physiological function. However, in addition to in vivo applications, there has been substantial recent interest in biomaterials for in vitro systems. Such artificial tissues and organs are employed in drug discovery, functional cell biological investigations, and basic research that would be ethically impossible to conduct in living women. This Roadmap is a collection of 11 sections written by leading and up-and-coming experts in this field who review and discuss four aspects of biomaterials for women’s health. These include conditions that disproportionately but not exclusively affect women (e.g. breast cancer), conditions unique to female reproductive organs, in both non-pregnant and pregnant states, and sex differences in non-reproductive tissues (e.g. the cardiovascular system). There is a strong need to develop this exciting field, with the potential to materially influence women’s lives worldwide.
Keywords
