Scientific Reports (Jun 2022)
The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution
- Yoshiki Kohmura,
- Shun-Min Yang,
- Hsiang-Hsin Chen,
- Hidekazu Takano,
- Chia-Ju Chang,
- Ya-Sian Wang,
- Tsung-Tse Lee,
- Ching-Yu Chiu,
- Kai-En Yang,
- Yu-Ting Chien,
- Huan-Ming Hu,
- Tzu-Ling Su,
- Cyril Petibois,
- Yi-Yun Chen,
- Cheng-Huan Hsu,
- Peilin Chen,
- Dueng-Yuan Hueng,
- Shean-Jen Chen,
- Chi Lin Yang,
- An-Lun Chin,
- Chian-Ming Low,
- Francis Chee Kuan Tan,
- Alvin Teo,
- Eng Soon Tok,
- Xu Xiang Cai,
- Hong-Ming Lin,
- John Boeckl,
- Anton P. Stampfl,
- Jumpei Yamada,
- Satoshi Matsuyama,
- Tetsuya Ishikawa,
- Giorgio Margaritondo,
- Ann-Shyn Chiang,
- Yeukuang Hwu
Affiliations
- Yoshiki Kohmura
- RIKEN/SPring-8 Center
- Shun-Min Yang
- Institute of Physics, Academia Sinica
- Hsiang-Hsin Chen
- Institute of Physics, Academia Sinica
- Hidekazu Takano
- RIKEN/SPring-8 Center
- Chia-Ju Chang
- Institute of Physics, Academia Sinica
- Ya-Sian Wang
- Institute of Physics, Academia Sinica
- Tsung-Tse Lee
- Institute of Physics, Academia Sinica
- Ching-Yu Chiu
- Institute of Physics, Academia Sinica
- Kai-En Yang
- Institute of Physics, Academia Sinica
- Yu-Ting Chien
- Institute of Physics, Academia Sinica
- Huan-Ming Hu
- Institute of Physics, Academia Sinica
- Tzu-Ling Su
- Institute of Physics, Academia Sinica
- Cyril Petibois
- Institute of Physics, Academia Sinica
- Yi-Yun Chen
- Institute of Physics, Academia Sinica
- Cheng-Huan Hsu
- Institute of Physics, Academia Sinica
- Peilin Chen
- Institute of Physics, Academia Sinica
- Dueng-Yuan Hueng
- Department of Surgery, School of Medicine, National Defense Medical Center
- Shean-Jen Chen
- College of Photonics, National Yang Ming Chiao Tung University
- Chi Lin Yang
- Brain Research Center, National Tsing Hua University
- An-Lun Chin
- Brain Research Center, National Tsing Hua University
- Chian-Ming Low
- Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore
- Francis Chee Kuan Tan
- Department of Anaesthesia, Yong Loo Lin School of Medicine, National University of Singapore
- Alvin Teo
- School of Chemical and Life Sciences, Nanyang Polytechnic
- Eng Soon Tok
- ƐMaGIC-Lab, Department of Physics, National University of Singapore
- Xu Xiang Cai
- Mechanical and Materials Department, Tatung University
- Hong-Ming Lin
- Mechanical and Materials Department, Tatung University
- John Boeckl
- US Air Force Research Laboratory, Materials and Manufacturing Directorate, WPAFB
- Anton P. Stampfl
- Australian Nuclear Science and Technology Organisation
- Jumpei Yamada
- RIKEN/SPring-8 Center
- Satoshi Matsuyama
- Department of Materials Physics, Graduate School of Engineering, Nagoya University
- Tetsuya Ishikawa
- RIKEN/SPring-8 Center
- Giorgio Margaritondo
- Ecole Polytechnique Fédérale de Lausanne
- Ann-Shyn Chiang
- Institute of Physics, Academia Sinica
- Yeukuang Hwu
- Institute of Physics, Academia Sinica
- DOI
- https://doi.org/10.1038/s41598-022-13377-w
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 10
Abstract
Abstract Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging and high throughput. An ultrathin, laminar X-ray beam produced by a Wolter type I mirror irradiates the sample stimulating the emission of visible light by scintillating nanoparticles, captured by an optical system. Three-dimensional (3D) images are obtained by scanning the specimen with respect to the laminar beam. We implemented and tested the technique with a high-brightness undulator at SPring-8, demonstrating its validity for a variety of specimens. This work was performed under the Synchrotrons for Neuroscience—an Asia–Pacific Strategic Enterprise (SYNAPSE) collaboration.
