Nature Communications (Feb 2018)

Elucidation of the origin of chiral amplification in discrete molecular polyhedra

  • Yu Wang,
  • Hongxun Fang,
  • Ionut Tranca,
  • Hang Qu,
  • Xinchang Wang,
  • Albert J. Markvoort,
  • Zhongqun Tian,
  • Xiaoyu Cao

DOI
https://doi.org/10.1038/s41467-017-02605-x
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 8

Abstract

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The sergeants-and-soldiers effect, in which a few chiral units induce chirality in a large number of achiral molecules, is difficult to quantify at the molecular level. Here, the authors devise an elegant strategy—combining theory and a system of pure organic polyhedra with chiral and achiral vertices—to understand the mechanism of chiral amplification in discrete molecular assemblies.