Clinical Interventions in Aging (May 2024)
Addressing the Missing Links in Cardiovascular Aging
Abstract
Elliot Dinetz,1 Claudia Zeballos-Palacios,2 Claudia A Martinez3 1Department of Integrative and Family Medicine, University of Miami Miller School of Medicine Miami, Miami, FL, USA; 2Department of Knowledge and Evaluation Research Unit, Mayo Clinic, Rochester, MN, USA; 3Department of Medicine, Cardiovascular Division, University of Miami Miller School of Medicine, Miami, FL, USACorrespondence: Elliot Dinetz, Tel +786.490.5915, Email [email protected]: The aim of this manuscript is to provide a review of available options to enhance cardiovascular health and prevent cardiovascular disease (CVD) in the aging population using a systems-biology approach. These include the role of the gut microbiome, the early identification and removal of environmental toxins, and finally age related sex hormones and supplement replacement which all influence aging. Implementing such a comprehensive approach has the potential to facilitate earlier risk assessment, disease prevention, and even improve mortality. Further study in these areas will continue to advance our understanding and refine therapeutic interventions for a healthier cardiovascular aging process.Keywords: vascular aging, cardiovascular aging, inflammaging, systems biology medicine, microbiome, toxic metals, bioidentical hormone replacement
