Organic Synthesis with ?-Silylcarbonyl Compounds

Abstract

Our interest in organosilicon compounds has led us to examine the chemistry of rarely used ?-silylcarbonyl compounds. Possible applications of these synthons are not covered totally here, but a few examples along these lines should demonstrate the utility of these structurally simple substrates in organic synthesis. The preparation of the ?-silyl esters and some examples of their stereocontrolled conversion into polysubstituted tetrahydrofurans is presented.