Atrial angiotensin-(1-12)/chymase expression data in patient of heart diseases

Hao Wang; Jasmina Varagic; Sayaka Nagata; Neal D. Kon; Sarfaraz Ahmad; Jessica L. VonCannon; Kendra N. Wright; Xuming Sun; Dwight Deal; Leanne Groban; Carlos M. Ferrario

Data in Brief (Aug 2020)

Atrial angiotensin-(1-12)/chymase expression data in patient of heart diseases

Hao Wang,
Jasmina Varagic,
Sayaka Nagata,
Neal D. Kon,
Sarfaraz Ahmad,
Jessica L. VonCannon,
Kendra N. Wright,
Xuming Sun,
Dwight Deal,
Leanne Groban,
Carlos M. Ferrario

Affiliations

Hao Wang: Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Internal Medicine-Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA; Corresponding Author: Hao Wang, MD, PhD, Department of Anesthesiology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157-1009, Phone: 336-716-4498, Fax: 336-716-8190.
Jasmina Varagic: Department of Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA; Hypertension and Vascular Research Center, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Physiology & Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC, USA
Sayaka Nagata: Department of Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA
Neal D. Kon: Department of Cardiothoracic Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA
Sarfaraz Ahmad: Department of Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA
Jessica L. VonCannon: Department of Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA
Kendra N. Wright: Department of Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA
Xuming Sun: Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA
Dwight Deal: Department of Cardiothoracic Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA
Leanne Groban: Department of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Internal Medicine-Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA
Carlos M. Ferrario: Department of Surgery, Wake Forest School of Medicine, Winston-Salem, NC, USA; Department of Physiology & Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC, USA

Journal volume & issue: Vol. 31
p. 105744

Abstract

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The data presented here are related to the research article entitled “Differential expression of the angiotensin-(1-12) [Ang-(1-12)]/chymase axis in human atrial tissue [1]. We have showed that chymase gene transcripts, chymase activity, and immunoreactive- Ang-(1-12) expression levels were higher in left compared to right atrial tissue, irrespective of cardiac disease. This article presents the echocardiographic characteristics of 111 patients undergoing heart surgery for the correction of valvular heart disease, resistant atrial fibrillation or ischemic heart disease. Left atrial chymase mRNA expression and activity, and left atrial Ang-(1-12) levels were compared between patients with stroke vs. non-stroke, congestive heart failure vs. non-heart failure, and in cardiac surgery patients who had a history of postoperative atrial fibrillation vs. non-atrial fibrillation.

Published in Data in Brief

ISSN: 2352-3409 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Computer applications to medicine. Medical informatics; Science: Science (General)
Website: http://www.journals.elsevier.com/data-in-brief/

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