Nature Communications (Jan 2021)
Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy
- Mary Prahl,
- Pamela Odorizzi,
- David Gingrich,
- Mary Muhindo,
- Tara McIntyre,
- Rachel Budker,
- Prasanna Jagannathan,
- Lila Farrington,
- Mayimuna Nalubega,
- Felistas Nankya,
- Esther Sikyomu,
- Kenneth Musinguzi,
- Kate Naluwu,
- Ann Auma,
- Abel Kakuru,
- Moses R. Kamya,
- Grant Dorsey,
- Francesca Aweeka,
- Margaret E. Feeney
Affiliations
- Mary Prahl
- Department of Pediatrics, University of California San Francisco
- Pamela Odorizzi
- Department of Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco
- David Gingrich
- Department of Clinical Pharmacy, University of California San Francisco, Drug Research Unit
- Mary Muhindo
- Infectious Diseases Research Collaboration
- Tara McIntyre
- Department of Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco
- Rachel Budker
- Department of Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco
- Prasanna Jagannathan
- Department of Medicine, Stanford University
- Lila Farrington
- Department of Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco
- Mayimuna Nalubega
- Infectious Diseases Research Collaboration
- Felistas Nankya
- Infectious Diseases Research Collaboration
- Esther Sikyomu
- Infectious Diseases Research Collaboration
- Kenneth Musinguzi
- Infectious Diseases Research Collaboration
- Kate Naluwu
- Infectious Diseases Research Collaboration
- Ann Auma
- Infectious Diseases Research Collaboration
- Abel Kakuru
- Infectious Diseases Research Collaboration
- Moses R. Kamya
- Infectious Diseases Research Collaboration
- Grant Dorsey
- Department of Medicine, Zuckerberg San Francisco General Hospital, University of California San Francisco
- Francesca Aweeka
- Department of Clinical Pharmacy, University of California San Francisco, Drug Research Unit
- Margaret E. Feeney
- Department of Pediatrics, University of California San Francisco
- DOI
- https://doi.org/10.1038/s41467-020-20475-8
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 8
Abstract
Control of mosquito populations using pesticides is important for malaria elimination, but effects of pesticides on humans aren’t well understood. Here, Prahl et al. show in a cohort of pregnant Ugandan women and their infants that household spraying with bendiocarb affects the fetal immune system and response to vaccination in infancy.
