Emerging Infectious Diseases (Dec 2016)

Genetically Different Highly Pathogenic Avian Influenza A(H5N1) Viruses in West Africa, 2015

  • Luca Tassoni,
  • Alice Fusaro,
  • Adelaide Milani,
  • Philippe Lemey,
  • Joseph Adongo Awuni,
  • Victoria Bernice Sedor,
  • Otilia Dogbey,
  • Abraham Nii Okai Commey,
  • Clement Meseko,
  • Tony Joannis,
  • Germaine Minoungou,
  • Lassina Ouattara,
  • Abdoul Malick Haido,
  • Diarra Cisse-Aman,
  • Emmanuel Couacy-Hymann,
  • Gwenaelle Dauphin,
  • Giovanni Cattoli,
  • Isabella Monne

DOI
https://doi.org/10.3201/eid2212.160578
Journal volume & issue
Vol. 22, no. 12
pp. 2132 – 2136

Abstract

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To trace the evolution of highly pathogenic influenza A(H5N1) virus in West Africa, we sequenced genomes of 43 viruses collected during 2015 from poultry and wild birds in 5 countries. We found 2 co-circulating genetic groups within clade 2.3.2.1c. Mutations that may increase adaptation to mammals raise concern over possible risk for humans.

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