Evaluation of Xpert MTB/RIF Assay on Stool Samples for the Diagnosis of Pulmonary Tuberculosis among the Pediatric Population

Sangitha Jayagandan; Jitendra Singh; Shivkumar Rashmi Mudliar; Prem Shankar; Anand Kumar Maurya; Anvita Gupta Malhotra; Shikha Malik; Shashank Purwar; Sarman Singh

doi:10.1055/s-0042-1757721

Journal of Laboratory Physicians (Sep 2023)

Evaluation of Xpert MTB/RIF Assay on Stool Samples for the Diagnosis of Pulmonary Tuberculosis among the Pediatric Population

Sangitha Jayagandan,
Jitendra Singh,
Shivkumar Rashmi Mudliar,
Prem Shankar,
Anand Kumar Maurya,
Anvita Gupta Malhotra,
Shikha Malik,
Shashank Purwar,
Sarman Singh

Affiliations

Sangitha Jayagandan: ORCiD; Department of Microbiology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
Jitendra Singh: ORCiD; Department of Translational Medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
Shivkumar Rashmi Mudliar: Department of Microbiology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
Prem Shankar: ORCiD; Department of Microbiology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
Anand Kumar Maurya: ORCiD; Department of Microbiology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
Anvita Gupta Malhotra: ORCiD; Department of Microbiology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
Shikha Malik: Department of Paediatrics, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
Shashank Purwar: ORCiD; Department of Microbiology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India
Sarman Singh: ORCiD; Former Director, All India Institute of Medical Sciences, Bhopal, India

DOI: https://doi.org/10.1055/s-0042-1757721
Journal volume & issue: Vol. 15, no. 03
pp. 329 – 335

Abstract

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Objective Microbiological confirmation of tuberculosis (TB) in pediatric cases is challenging due to its paucibacillary nature and difficulty in specimen collection. This study aimed to validate stool as an alternative sample for the diagnosis of pediatric pulmonary TB via Xpert MTB/RIF (Xpert) assay.

Published in Journal of Laboratory Physicians

ISSN: 0974-2727 (Print); 0974-7826 (Online)
Publisher: Thieme Medical and Scientific Publishers Pvt. Ltd.
Country of publisher: India
LCC subjects: Medicine
Website: https://www.thieme.in/journal-of-laboratory-physicians

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