The aim of the research – to examine the course of pregnancy, childbirth and the postpartum period in patients with HPV infection combined with bacterial vaginosis. Materials and methods. A survey of 100 pregnant women (main group) with PVI in combination with bacterial vaginosis, their newborns. To study the effect of the magnitude of viral load during pregnancy, the main group was divided into two podgruppy: Ia main group - women with viral loads of up to 5 lg per 100000 host cells (n = 37), Ib main group – more 5 lg per 100000 host cells (n = 63). The control group consisted of 50 pregnant women without vaginal infection. Results. In the main group in 47 % of cases, the changes were seen as LSIL (intraepithelial lesion mild), 18 % of women, the changes were consistent with the category of HSIL (intraepithelial lesion of high degree), 15 % of pregnant Cytology classified as ASCUS (squamous cells of uncertain significance) and only 20 % of patients, PAP smears were consistent with NILM class. The high frequency of abnormal colposcopic pictures of the cervix in pregnant women of the main group (65 %). Patients with high load of HPV and bacterial vaginosis most births were complicated by antenatal discharge of amniotic fluid and soft tissue injuries of the birth canal. Conclusion. Pregnancy in patients with HPV infection on the background of bacterial vaginosis significantly more often complicated by threatened abortion, premature birth, untimely discharge of amniotic fluid, soft tissue injuries of the birth canal. Risk factors for transmission of human papilloma virus was birth vaginally and duration of waterless period of more than 6 hours. The frequency of detection of human papillomavirus from mothers with papilloma infection and bacterial vaginosis in newborns was 38 %.