A COMPLETE NMR STUDY OF DOXAZOSIN CHARACTERIZATION

Abstract

Doxazosin is an important drug used for treating hypertension and prostatic hyperplasia. An enantiomeric mixture (R)/(S) doxazosin mesylate was complete characterized by NMR and additionally FT-IR spectroscopy techniques. Were performed different NMR experiments, such as APT, HSQC, and HMBC in order to confirm the NMR signals assignments. All the hydrogens and the most of carbons atoms were assigned.

Keywords

• doxazosin
• nmr
• ft-ir
• signals assignment