Mediterranean Journal of Hematology and Infectious Diseases (Jan 2020)

CARDIOVASCULAR RISK IN ESSENTIAL THROMBOCYTHEMIA AND POLYCYTHEMIA VERA: THROMBOTIC RISK AND SURVIVAL

  • Vincenzo Accurso,
  • Marco Santoro,
  • Salvatrice Mancuso,
  • Angelo Davide Contrino,
  • Paolo Casimio,
  • Mariano Sardo,
  • Simona Raso,
  • Florinda Di Piazza,
  • Alessandro Perez,
  • Marco Bono,
  • Antonio Russo,
  • Sergio Siragusa

DOI
https://doi.org/10.4084/mjhid.2020.008
Journal volume & issue
Vol. 12, no. 1

Abstract

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Abstract Thromboembolic and bleeding events pose a severe risk for patients with Polycythemia Vera (PV) and Essential Thrombocythemia (ET). Many factors can contribute to determine the thrombotic event, including the interaction between platelets, leukocytes and endothelium alterations. Moreover, a very important role can be played by cardiovascular risk factors (CV.R) such as cigarette smoking habits, hypertension, diabetes, obesity and dyslipidemia. In this study we evaluated the impact that CV.R plays on thrombotic risk and survival in patients with PV and ET.

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