Formation of physiologic atresia in combination with development of esophageal epithelium

Abstract

In five weeks embryos as a result of the active proliferation of epithelium of esophageal mucous membrane occurs so-called physiological atresia of organ. Epithelium of the mucous membrane and esophageal glands has entodermal origin. In 6-7-weeks embryos structural changes in epithelial esophageal layer were observed. At the end of the embryonic period the differentiation of mesenchimal cells which surrounding of esophageal mucous membrane are taking place, some of them are lengthening and located concentrically, which should be consider of the beginning of circular layer of the esophageal mucous membrane. In prefetuses of 45,0-50,0 mm PCL (10-th week) esophageal mucous membrane is represented mainly by two-layered cylindrical epithelium. Recanalization of the esophageal gap begins and ends in prefetuses of 7-10 weeks.

Keywords

• physiologic atresia
• embryos
• prefetuses
• epithelium
• esophagus