Galleria mellonella immune melanization is fungicidal during infection

Daniel F. Q. Smith; Quigly Dragotakes; Madhura Kulkarni; J. Marie Hardwick; Arturo Casadevall

doi:10.1038/s42003-022-04340-6

Communications Biology (Dec 2022)

Galleria mellonella immune melanization is fungicidal during infection

Daniel F. Q. Smith,
Quigly Dragotakes,
Madhura Kulkarni,
J. Marie Hardwick,
Arturo Casadevall

Affiliations

Daniel F. Q. Smith: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health
Quigly Dragotakes: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health
Madhura Kulkarni: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health
J. Marie Hardwick: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health
Arturo Casadevall: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health

DOI: https://doi.org/10.1038/s42003-022-04340-6
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 13

Abstract

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Real-time imaging of fungal infection and tissue clearing in the wax moth, Galleria mellonella, help evaluate the role of melanin in the insect host immune response to fungal pathogens.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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