Pharmaceutical perspectives of thiazole analogues: An overview

Archana R. Patil; Basappa C. Yallur; Sampath Chinnam; Guddekoppa S. Ananthnag; C.R. Santhosh; Geetika Pant; S.G. Prasanna Kumar; Manjuanth D. Hadagali

Results in Chemistry (Dec 2024)

Pharmaceutical perspectives of thiazole analogues: An overview

Archana R. Patil,
Basappa C. Yallur,
Sampath Chinnam,
Guddekoppa S. Ananthnag,
C.R. Santhosh,
Geetika Pant,
S.G. Prasanna Kumar,
Manjuanth D. Hadagali

Affiliations

Archana R. Patil: Department of Chemistry, M.S. Ramaiah Institute of Technology, Bengaluru, Karnataka 560054, India
Basappa C. Yallur: Department of Chemistry, M.S. Ramaiah Institute of Technology, Bengaluru, Karnataka 560054, India; Corresponding authors.
Sampath Chinnam: Department of Chemistry, M.S. Ramaiah Institute of Technology, Bengaluru, Karnataka 560054, India; Corresponding authors.
Guddekoppa S. Ananthnag: Department of Chemistry, B.M.S. College of Engineering, Bull Temple Road, Bengaluru, Karnataka 560019, India
C.R. Santhosh: Department of Chemistry, M.S. Ramaiah Institute of Technology, Bengaluru, Karnataka 560054, India
Geetika Pant: Department of Biotechnology & Genetics, M.S. Ramaiah College of Arts, Science and Commerce, Bengaluru, Karnataka 560054, India
S.G. Prasanna Kumar: Department of Chemistry, M.S. Ramaiah College of Arts, Science and Commerce, Bengaluru, Karnataka 560054, India
Manjuanth D. Hadagali: Department of Studies in Chemistry, Davangere University, Karnataka, India

Journal volume & issue: Vol. 12
p. 101820

Abstract

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Thiazole derivatives have attracted considerable attention in medicinal chemistry due to their promising biological activities. This review article provides a comprehensive overview on the pharmaceutical applications of the thiazole derivatives, exploring their structural activity relationship and medical applications. We discuss the anti-cancer, anti-inflammatory, anti- oxidant, BSA and DNA interaction properties of thiazole derivatives highlighting their role in drug development. This review will be a valuable resource in medicinal chemistry. This could lead to development of drugs containing thiazoles and improve bio-compatibility and efficiency of derivatives.

Published in Results in Chemistry

ISSN: 2211-7156 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Science: Chemistry
Website: https://www.journals.elsevier.com/results-in-chemistry/

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