Synthesis of Diverse 11- and 12-Membered Macrolactones from a Common Linear Substrate Using a Single Biocatalyst

• Michael M. Gilbert,
• Matthew D. DeMars,
• Song Yang,
• Jessica M. Grandner,
• Shoulei Wang,
• Hengbin Wang,
• Alison R. H. Narayan,
• David H. Sherman,
• K. N. Houk,
• John Montgomery

Affiliations

Michael M. Gilbert

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States

Matthew D. DeMars

Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States

Song Yang

Department of Chemistry and Biochemistry, University of California, Los Angeles, California, United States

Jessica M. Grandner

Department of Chemistry and Biochemistry, University of California, Los Angeles, California, United States

Shoulei Wang

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States

Hengbin Wang

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States

Alison R. H. Narayan

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States

David H. Sherman

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States

K. N. Houk

Department of Chemistry and Biochemistry, University of California, Los Angeles, California, United States

John Montgomery

Department of Chemistry, University of Michigan, Ann Arbor, Michigan, United States