Nature Communications (Mar 2023)

Association of SARS-CoV-2 BA.4/BA.5 Omicron lineages with immune escape and clinical outcome

  • Joseph A. Lewnard,
  • Vennis Hong,
  • Jeniffer S. Kim,
  • Sally F. Shaw,
  • Bruno Lewin,
  • Harpreet Takhar,
  • Sara Y. Tartof

DOI
https://doi.org/10.1038/s41467-023-37051-5
Journal volume & issue
Vol. 14, no. 1
pp. 1 – 11

Abstract

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Continuous monitoring of SARS-CoV-2 variant properties is important for public health planning. Here, the authors use data from the United States and show that Omicron BA.4/5 subvariants, which became dominant in mid-2022, have stronger immune escape properties, but are no more severe, than the previously dominant BA.2.