Recent Advances of Upconversion Nanomaterials in the Biological Field
Cunjin Gao,
Pengrui Zheng,
Quanxiao Liu,
Shuang Han,
Dongli Li,
Shiyong Luo,
Hunter Temple,
Christina Xing,
Jigang Wang,
Yanling Wei,
Tao Jiang,
Wei Chen
Affiliations
Cunjin Gao
Beijing Key Laboratory of Printing and Packaging Materials and Technology, Beijing Institute of Graphic Communication, Beijing 102600, China
Pengrui Zheng
Beijing Key Laboratory of Printing and Packaging Materials and Technology, Beijing Institute of Graphic Communication, Beijing 102600, China
Quanxiao Liu
Beijing Key Laboratory of Printing and Packaging Materials and Technology, Beijing Institute of Graphic Communication, Beijing 102600, China
Shuang Han
Beijing Key Laboratory of Printing and Packaging Materials and Technology, Beijing Institute of Graphic Communication, Beijing 102600, China
Dongli Li
Beijing Key Laboratory of Printing and Packaging Materials and Technology, Beijing Institute of Graphic Communication, Beijing 102600, China
Shiyong Luo
Beijing Key Laboratory of Printing and Packaging Materials and Technology, Beijing Institute of Graphic Communication, Beijing 102600, China
Hunter Temple
Department of Physics, The University of Texas at Arlington, Arlington, TX 76019-0059, USA
Christina Xing
Department of Physics, The University of Texas at Arlington, Arlington, TX 76019-0059, USA
Jigang Wang
Beijing Key Laboratory of Printing and Packaging Materials and Technology, Beijing Institute of Graphic Communication, Beijing 102600, China
Yanling Wei
Faculty of Applied Sciences, Jilin Engineering Normal University, Changchun 130052, China
Tao Jiang
CAS Center for Excellence in Nanoscience, Beijing Key Laboratory of Micro-Nano Energy and Sensor, Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 101400, China
Wei Chen
Department of Physics, The University of Texas at Arlington, Arlington, TX 76019-0059, USA
Rare Earth Upconversion nanoparticles (UCNPs) are a type of material that emits high-energy photons by absorbing two or more low-energy photons caused by the anti-stokes process. It can emit ultraviolet (UV) visible light or near-infrared (NIR) luminescence upon NIR light excitation. Due to its excellent physical and chemical properties, including exceptional optical stability, narrow emission band, enormous Anti-Stokes spectral shift, high light penetration in biological tissues, long luminescent lifetime, and a high signal-to-noise ratio, it shows a prodigious application potential for bio-imaging and photodynamic therapy. This paper will briefly introduce the physical mechanism of upconversion luminescence (UCL) and focus on their research progress and achievements in bio-imaging, bio-detection, and photodynamic therapy.