The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut

• Rana Ramadan,
• Valérie M. Wouters,
• Sanne M. van Neerven,
• Nina E. de Groot,
• Tania Martins Garcia,
• Vanessa Muncan,
• Olivia D. Franklin,
• Michelle Battle,
• Karen Sue Carlson,
• Joshua Leach,
• Owen J. Sansom,
• Olivier Boulard,
• Mathias Chamaillard,
• Louis Vermeulen,
• Jan Paul Medema,
• David J. Huels

Affiliations

Rana Ramadan

Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

Valérie M. Wouters

Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

Sanne M. van Neerven

Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

Nina E. de Groot

Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

Tania Martins Garcia

Department of Gastroenterology and Hepatology, Tytgat Institute for Intestinal and Liver Research, Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam UMC University of Amsterdam, 1015 BK Amsterdam, The Netherlands

Vanessa Muncan

Department of Gastroenterology and Hepatology, Tytgat Institute for Intestinal and Liver Research, Amsterdam Gastroenterology Endocrinology and Metabolism, Amsterdam UMC University of Amsterdam, 1015 BK Amsterdam, The Netherlands

Olivia D. Franklin

The Medical College of Wisconsin, Department of Cell Biology, Neurobiology, and Anatomy, Milwaukee, WI 53226, USA

Michelle Battle

The Medical College of Wisconsin, Department of Cell Biology, Neurobiology, and Anatomy, Milwaukee, WI 53226, USA

Karen Sue Carlson

The Medical College of Wisconsin, Department of Cell Biology, Neurobiology, and Anatomy, Milwaukee, WI 53226, USA

Joshua Leach

Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK

Owen J. Sansom

Cancer Research UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK

Olivier Boulard

CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 – UMR 8204 – Centre d'Infection et d'Immunité de Lille (CIIL), Université de Lille, 59019 Lille, France

Mathias Chamaillard

CNRS, Inserm, CHU Lille, Institut Pasteur de Lille, U1019 – UMR 8204 – Centre d'Infection et d'Immunité de Lille (CIIL), Université de Lille, 59019 Lille, France

Louis Vermeulen

Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

Jan Paul Medema

Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands

David J. Huels

Laboratory for Experimental Oncology and Radiobiology, Center for Experimental and Molecular Medicine, Cancer Center Amsterdam, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands