Targeted Treatment Trastuzumab is found to greatly Improve Long Term Survival of HER2 Breast Cancer Patients

Abstract

The goal of this study is to assess the importance of adding adjuvant TRASTUZUMAB as a standard in her2 overexpressed breast cancer. Fifty female patients have known to be HER2 overexpressed breast cancer, recruited from the clinical oncology clinic at Beni-Suef University Hospital, and from the insurance hospital at Beni-Suef city. This is a retrospective study. This study was done within six months. The results of this trial indicate that one year of adjuvant trastuzumab should be considered a standard on completion of locoregional therapy and neoadjuvant or adjuvant chemotherapy. That study indicated that adding trastuzumab to chemotherapy had improved overall survival &disease free survival, all the recruited patients in that study were still alive till the end of the study and about 8% (n=4) vs 92% (n=46) of patients developed distant recurrences. Receiving adjuvant TRASTUZUMAB for 1year without delaying in initiation (≤ 6 months) after diagnosis, offers dramatic effects on overall survival OS and disease free survival DFS.

Keywords

• disease-free survival (dfs)
• overall survival (os)
• neoadjuvant chemotherapy