1506 A human SLE variant NCF1-R90H promotes kidney damage and murine lupus through enhanced Tfh2 responses induced by defective efferocytosis of macrophages

• Gary S Gilkeson,
• Jian Zhao,
• Betty P Tsao,
• Phillip Ruiz,
• Yun Deng,
• Quan-Zhen Li,
• Diane Kamen,
• Ivan Molano,
• Xue Xu,
• Lin-Yu Geng,
• Ling-Xiao Xu,
• Xue-Bing Feng,
• Miao-Jia Zhang,
• Wen-Feng Tan,
• Ling-Yun Sun

Affiliations

Gary S Gilkeson

3 Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA

Jian Zhao

Department of Nutrition and Food Safety, School of Population Medicine and Public Health, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

Betty P Tsao

Division of Rheumatology, University of California Los Angeles, Los Angeles, California, USA

Phillip Ruiz

Departments of Surgery and Pathology, University of Miami Miller School of Medicine, Miami, Florida, USA

Yun Deng

1Division of Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA

Quan-Zhen Li

1Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX, USA

Diane Kamen

6Department of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA

Ivan Molano

1MUSC

Xue Xu

Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA

Lin-Yu Geng

1Division of Rheumatology and Immunology, Medical University of South Carolina, SC, USA

Ling-Xiao Xu

1Division of Rheumatology and Immunology, Medical University of South Carolina, SC, USA

Xue-Bing Feng

2Department of Rheumatology and Immunology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China

Miao-Jia Zhang

5Department of Rheumatology, the First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China

Wen-Feng Tan

5Department of Rheumatology, the First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Road, Nanjing 210029, China

Ling-Yun Sun

2Department of Rheumatology and Immunology, the Affiliated Drum Tower Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing 210008, China