Thoracic Cancer (Apr 2021)

Primary signet‐ring cell carcinoma of the lung in an HIV‐positive patient

  • Alberto Testori,
  • Gianluca Perroni,
  • Camilla De Carlo,
  • Alessandro Crepaldi,
  • Marco Alloisio,
  • Ugo Cioffi

DOI
https://doi.org/10.1111/1759-7714.13887
Journal volume & issue
Vol. 12, no. 7
pp. 1122 – 1125

Abstract

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Abstract Primary lung signet‐ring cell carcinomas are a rare entity and only a few cases of pure signet‐ring cell carcinomas of the lung are reported in the English literature. They usually have an aggressive behavior and a poor prognosis because in most cases they are identified at an advanced stage. We present a unique case of primary signet‐ring cell carcinoma of the lung because the patient was HIV positive, a heavy smoker, and also the tumor, discovered incidentally during chest x‐ray, was a pure type of signet‐ring cell carcinoma. Surgical therapy associated with chemoradiotherapy represents the gold standard in the care of these patients.

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