Invasive Streptococcus oralis Expressing Serotype 3 Pneumococcal Capsule, Japan

Abstract

We report 2 adult cases of invasive disease in Japan caused by Streptococcus oralis that expressed the serotype 3 pneumococcal capsule and formed mucoid colonies. Whole-genome sequencing revealed that the identical serotype 3 pneumococcal capsule locus and hyl fragment were recombined into the genomes of 2 distinct S. oralis strains.

Keywords

• Streptococci
• bacteria
• Streptococcus oralis
• serotype 3 pneumococcal capsule
• mucoid phenotype
• multifragment recombination