PLoS ONE (Jan 2021)

In-hospital mortality among consecutive patients with ST-Elevation myocardial infarction in modern primary percutaneous intervention era ~ Insights from 15-year data of single-center hospital-based registry ~.

  • Kensuke Takagi,
  • Akihito Tanaka,
  • Naoki Yoshioka,
  • Yasuhiro Morita,
  • Ruka Yoshida,
  • Yasunori Kanzaki,
  • Naoki Watanabe,
  • Ryota Yamauchi,
  • Shotaro Komeyama,
  • Hiroki Sugiyama,
  • Kazuki Shimojo,
  • Takuro Imaoka,
  • Gaku Sakamoto,
  • Takuma Ohi,
  • Hiroki Goto,
  • Hideki Ishii,
  • Itsuro Morishima,
  • Toyoaki Murohara

DOI
https://doi.org/10.1371/journal.pone.0252503
Journal volume & issue
Vol. 16, no. 6
p. e0252503

Abstract

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ObjectiveTo clarify the association of detailed angiographic findings with in-hospital outcome after primary percutaneous coronary intervention (p-PCI) for ST-elevation myocardial infarction (STEMI) in Japan.BackgroundData regarding the association of detailed angiographic findings with in-hospital outcome after STEMI are limited in the p-PCI era.MethodsBetween January-2004 and December-2018, 1735 patients with STEMI (mean age, 68.5 years; female, 24.6%) who presented to the hospital in the 24-hours after symptom onset and underwent p-PCI were evaluated using the disease registries. The registry is an ongoing, retrospective, single-center hospital-based registry.ResultsThe 30-day mortality rate and in-hospital mortality rate were 7.7% and 9.2%, respectively. Independent predictors of in-hospital mortality were ejection fraction (EF) II (aOR, 7.438; p ConclusionsAmong the consecutive patients with STEMI, the in-hospital mortality rate after p-PCI significantly improved in the second half. Not only CKD, Killip class > II, and EF < 40%, but also the angiographic findings such as culprit lesions in the LCA, absence of very robust collaterals, and final TIMI grades <3 were associated with an increased risk of in-hospital mortality.