Variables That Affect Results of PFA-100 in a Group of Healthy Blood Donors in the Slovak Population

Abstract

Background: The platelet function analyzer (PFA-100) is a system analyzing platelet function determined for detection of the functional inherited and acquired platelet disorders, screening of von Willebrand disease (vWD) and recently also considered as useful for monitoring of antiplatelet treatment. The PFA-100 test uses a high shear flow system to simulate in vitro the conditions to which platelets are subjected at the site of a damaged blood vessel wall.

Keywords

• platelet function analyzer (pfa-100)
• closure time (ct)
• collagen/epinephrine (cepi)
• collagen/adp (cadp)
• blood group
• gender