Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)

Hiroshi Qadota; Annie McPherson; Rachel Corbitt; Evan Kelton Dackowski; Yohei Matsunaga; Andres F Oberhauser; Guy M Benian

doi:10.1093/g3journal/jkac117

G3: Genes, Genomes, Genetics (May 2022)

Genetic analysis suggests a surface of PAT-4 (ILK) that interacts with UNC-112 (kindlin)

Hiroshi Qadota,
Annie McPherson,
Rachel Corbitt,
Evan Kelton Dackowski,
Yohei Matsunaga,
Andres F Oberhauser,
Guy M Benian

Affiliations

Hiroshi Qadota: ORCiD; Department of Pathology, Emory University, Atlanta, GA 30322, USA
Annie McPherson: Department of Pathology, Emory University, Atlanta, GA 30322, USA
Rachel Corbitt: Department of Pathology, Emory University, Atlanta, GA 30322, USA
Evan Kelton Dackowski: Department of Pathology, Emory University, Atlanta, GA 30322, USA
Yohei Matsunaga: Department of Pathology, Emory University, Atlanta, GA 30322, USA
Andres F Oberhauser: ORCiD; Department of Neuroscience, Cell Biology and Anatomy, University of Texas Medical Branch, Galveston, TX 77555, USA
Guy M Benian: ORCiD; Department of Pathology, Emory University, Atlanta, GA 30322, USA

DOI: https://doi.org/10.1093/g3journal/jkac117
Journal volume & issue: Vol. 12, no. 7

Abstract

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AbstractIntegrin plays a crucial role in the attachment of cells to the extracellular matrix. Integrin recruits many proteins intracellularly, including a 4-protein complex (kindlin, ILK, PINCH, and parvin). Caenorhabditis elegansCaenorhabditis elegans

Published in G3: Genes, Genomes, Genetics

ISSN: 2160-1836 (Online)
Publisher: Oxford University Press
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General): Genetics
Website: https://academic.oup.com/g3journal

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