European Journal of Medicinal Chemistry Reports (Apr 2024)
A review on the medicinal applications of flavonoids from aloe species
Abstract
The literature has examined the therapeutic properties of flavonoids found in Aloe species. According to reports, Aloe extracts exhibited antioxidant properties of flavonoids like genistein, isovitexin, isorhamnetin, and daidzenin. It has been reported that A. vera, A. arborescens, A. grandidentata, A. perfoliata, A. brevifolia, and A. saponaria all displayed anti-inflammatory therapeutic flavonoids such as vicenin 2, lucenin 2, orientin, and isovitexin. Aloe species extracts have antimicrobial qualities that prevent or stop the growth of germs due to the diverse range of chemicals they contain. Aloe hijazensis flavonoids had antifungal properties reported in the literature. The biological properties of Aloe flavonoids such as antioxidant, anti-inflammatory, antimicrobial, and anti-aging properties, are employed in the treatment and prevention of chronic diseases like diabetes, cancer, COVID-19, and others. Flavonoids derived from the genus Aloe are commonly utilized in pharmaceutical, nutraceutical, and cosmeceutical products for their medicinal potentials. Many flavonoids are proving to have therapeutic effects; however, the flavonoids of the Aloe species, which have been found and shown to have therapeutic properties, are still being thoroughly compiled. Thus, the current objective is to provide a comprehensive overview of the structures, categories, and analyses of the flavonoids that are present in medicinally useful Aloe species.
