International Medical Case Reports Journal (Feb 2024)

A Rare Manifestation of Secondary Hyperparathyroidism Due to Brown Tumors: A Case Report

  • Boudina M,
  • Zisimopoulou E,
  • Rakitzi P,
  • Barbanis S,
  • Syndouka E,
  • Zouli C,
  • Fotiadou A,
  • Stamati MS,
  • Balodimou C,
  • Christantoniou G,
  • Chrisoulidou A

Journal volume & issue
Vol. Volume 17
pp. 143 – 147

Abstract

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Maria Boudina,1 Eleana Zisimopoulou,1 Pantelitsa Rakitzi,1 Sotirios Barbanis,2 Eleni Syndouka,3 Chrysanthi Zouli,1 Aimilia Fotiadou,1 Mariana Stamati Stamati,1 Chrysanthi Balodimou,1 George Christantoniou,1 Alexandra Chrisoulidou1 1Department of Endocrinology, Theagenio Cancer Hospital, Thessaloniki, Greece; 2Department of Pathology, Theagenio Cancer Hospital, Thessaloniki, Greece; 3Department of Radiology, Theagenio Cancer Hospital, Thessaloniki, GreeceCorrespondence: Maria Boudina, Department of Endocrinology, Theagenio Cancer Hospital, Thessaloniki, Greece, Email [email protected]: Brown tumors, also known as cystic fibrosa, are rare, benign, osteolytic, fibrotic lesions of the bones that occur secondary to hyperparathyroidism. They are caused by increased osteoclastic activity leading to an abnormal bone metabolism.Case Description: Here, we present the case of a 58-year-old male, who presented with painful bony lesions, initially attributed to metastatic disease. After biochemical workout, imaging and biopsy, the nature of the lesions was revealed. We discuss the differential diagnosis and clinical management of the disease.Conclusion: Patients with brown tumors should be assessed in the differential diagnosis of bony lesions and should always be tested for hyperparathyroidism. An early diagnosis is crucial for the successful treatment of such patients.Keywords: brown tumor, hyperparathyroidism, chronic kidney disease, case report

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